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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRN3
All Species:
20.3
Human Site:
Y344
Identified Species:
37.22
UniProt:
Q9NYV6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYV6
NP_060897.3
651
74107
Y344
N
G
K
T
K
D
L
Y
R
D
L
I
N
I
F
Chimpanzee
Pan troglodytes
XP_001143837
595
67943
M312
S
C
H
V
Q
F
F
M
F
Y
L
C
S
F
K
Rhesus Macaque
Macaca mulatta
XP_001108222
651
74080
Y344
N
S
K
T
K
D
L
Y
R
D
L
I
N
I
F
Dog
Lupus familis
XP_536965
651
74211
Y344
N
N
K
T
K
D
L
Y
R
D
L
I
T
I
F
Cat
Felis silvestris
Mouse
Mus musculus
B2RS91
656
74499
Y342
N
N
K
T
K
D
L
Y
R
D
L
I
S
I
F
Rat
Rattus norvegicus
NP_001129318
661
75125
Y342
N
N
K
T
K
D
L
Y
R
D
L
I
S
I
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518561
660
75690
Y353
I
N
K
T
K
D
L
Y
R
D
L
I
A
I
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001107876
612
69642
V314
L
Y
R
D
L
L
A
V
F
D
K
L
I
L
P
Zebra Danio
Brachydanio rerio
XP_706962
612
68744
V314
L
Y
R
D
L
V
S
V
F
D
K
V
V
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788084
611
70731
F321
R
R
T
A
N
R
L
F
K
M
L
L
Y
L
F
Honey Bee
Apis mellifera
XP_001122533
483
56793
E201
P
R
L
E
L
D
N
E
E
E
D
L
M
D
D
Nematode Worm
Caenorhab. elegans
P48322
654
75091
L331
N
G
N
E
R
T
K
L
N
D
K
W
L
R
N
Sea Urchin
Strong. purpuratus
XP_784172
374
42533
L92
L
Q
V
F
E
S
V
L
L
P
T
H
A
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
97.6
90.6
N.A.
86.8
85.4
N.A.
76
N.A.
66.8
59.9
N.A.
29.7
27.7
24.4
28.5
Protein Similarity:
100
89
99
94.7
N.A.
92.9
91.8
N.A.
86
N.A.
79.8
76
N.A.
48.8
46.3
42.8
40.7
P-Site Identity:
100
6.6
93.3
86.6
N.A.
86.6
86.6
N.A.
80
N.A.
6.6
6.6
N.A.
20
6.6
20
0
P-Site Similarity:
100
26.6
93.3
86.6
N.A.
93.3
93.3
N.A.
80
N.A.
26.6
26.6
N.A.
46.6
20
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
0
0
0
16
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
16
0
54
0
0
0
70
8
0
0
8
8
% D
% Glu:
0
0
0
16
8
0
0
8
8
8
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
8
8
8
24
0
0
0
0
8
54
% F
% Gly:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
47
8
47
0
% I
% Lys:
0
0
47
0
47
0
8
0
8
0
24
0
0
0
8
% K
% Leu:
24
0
8
0
24
8
54
16
8
0
62
24
8
24
0
% L
% Met:
0
0
0
0
0
0
0
8
0
8
0
0
8
0
0
% M
% Asn:
47
31
8
0
8
0
8
0
8
0
0
0
16
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% P
% Gln:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
16
16
0
8
8
0
0
47
0
0
0
0
8
0
% R
% Ser:
8
8
0
0
0
8
8
0
0
0
0
0
24
8
8
% S
% Thr:
0
0
8
47
0
8
0
0
0
0
8
0
8
0
0
% T
% Val:
0
0
8
8
0
8
8
16
0
0
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
16
0
0
0
0
0
47
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _